Carcinoma de células de Merkel: patogénesis, manejo y tratamientos emergentes
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1.
Barquero Orias DE, Recinos DUL, Guevara JMS. Carcinoma de células de Merkel: patogénesis, manejo y tratamientos emergentes. Rev.méd.sinerg. [Internet]. 1 de mayo de 2019 [citado 29 de marzo de 2024];4(5):15 - 23. Disponible en: https://revistamedicasinergia.com/index.php/rms/article/view/189

Resumen

El carcinoma de células de Merkel es un tumor raro neuroendocrino, altamente agresivo con altas tasas de mortalidad asociadas a sus metástasis a distancia. Es más frecuente en pacientes inmunosupresos, edad avanzada y exposición a luz ultravioleta. La mayoría de asocian con Poliomavirus sin embargo existen casos sin presencia viral. Se recomienda la resección quirúrgica con márgenes extensos cuando se encuentra localizado y en casos seleccionados la biopsia de ganglio centinela. Es una neoplasia quimiosensible y radiosensible. Existen avances terapéuticos inmunológicos para casos avanzados.

https://doi.org/10.31434/rms.v4i5.189

Palabras clave

Poliomavirus de células de Merkel. neoplasias cutáneas. radioterapia. inmunoterapia.
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Citas

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