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Abstract
Inflammatory bowel disease is a complex, multifactorial, chronic inflammatory condition that has become more incident and prevalent in recent decades. Over the years, various drugs have been created to manage the disease, both during exacerbation and maintenance periods, with the primary objective of keeping it in remission. Since women of reproductive age are not excluded from the diagnosis, in case of pregnancy, it is necessary to define the most appropriate therapy, considering the maternal benefits of the treatment and the fetal risk that the therapy could have.
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References
Lima-Karagannis A, Zelinkova-Detkova Z, Janneke van der Woude C. The effects of active IBD during pregnancy in the era of novel IBD therapies. Am J Gastroenerol. 2016;111(9):1305-1312. https://doi.org/10.1038/ajg.2016.254
Van der Giessen J, Huang V, van der Woude J, Fuhler G. Modulatory effects of pregnancy on inflammatory bowel disease. Clin Transl Gastro. 2019;10:e-00009. https://doi.org/10.14309/ctg.0000000000000009
Mahadevan U, Robinson C, Bernasko N, Boland B, Chambers C, Dubinsky M, et al. Inflammatory bowel disease in pregnancy clinical care pathway: a report from the American Gastroenterological Association IBD parenthood project working group. Gastroenterology. 2019;156:1508-1524. https://doi.org/10.1053/j.gastro.2018.12.022
Koslowsky B, Grisaru-Granovsky S, Livovsky DM, Milgrom Y, Goldin E. Pregnanacy-Onset inflammatory bowel disease: a subtle diagnosis. Inflamm Bowel Dis. 2018; 24(8):1826-1832.
https://doi.org/10.1093/ibd/izy081
Singh S, Picardo S, Seow C. Management of Inflammatory Bowel Diseases in Special Populations: Obese, Old, or Obstetric. Clinical Gastroenterol and Hepatol. 2020; 18(6): 1367-1380. https://doi.org/10.1016/j.cgh.2019.11.009
McConnell R, Mahadevan U. Pregnancy and the patient with inflammatory bowel disease: fertility, treatment, delivery and complications. Gastroenterol Clin N Am. 2016;45:285-301.
https://doi.org/10.1016/j.gtc.2016.02.006
Jameson JL, Fauci AS, Kasper DL, Hauser SL, Longo DL, Loscalzo J. Harrison's Principles of Internal Medicine. 20 ed. New York: McGraw-Hill; 2018.
Feldman M, Friedman LS, Brandt LJ. Sleisenger and Fordtran's Gastrointestinal and Liver Disease. 10 ed. Philadelphia: Elsevier; 2016.
Quingdong Guan. A Comprehensive Review and Update on the Pathogenesis of Inflammatory Bowel Disease. J Immunol Res. 2019 (2019). https://doi.org/10.1155/2019/7247238
Peppercorn MA, Cheifetz AS. Definitions, epidemiology, and risk factors for inflammatory bowel disease in adults. Uptodate. [Internet] [Consultado 8 de abril del 2020] 2019; 05-01. Disponible en: https://www.uptodate.com/contents/definitions-epidemiology-and-risk-factors-for-inflammatory-bowel-disease-in-adults
Van der Giessen J, Binyamin D, Belogolovski A, Frishman S, Tenenbaum-Gavish K, Hadar E, et al. Modulation of cytokine patterns and microbiome during pregnancy in IBD. Gut. 2020;69:473-486. https://doi.org/10.1136/gutjnl-2019-318263
Fuhler G. The immune system and microbiome in pregnancy. Best Practice & Research Clinical Gastroenterology. 2020;44-45 (2020):101671. https://doi.org/10.1016/j.bpg.2020.101671
Rubin, DT, Ananthakrishnan AN, Siegel CA, Sauer BG, Long MD. ACG Clinical Guideline: Ulcerative Colitis in Adults. Am J Gastroenterol. 2019; 114(3):384-413. https://doi.org/10.14309/ajg.0000000000000152
Lichtenstein GR, Loft us Jr EV, Isaacs KL, Regueiro MD, Gerson LB, Sands BE. ACG Clinical Guideline: Management of Crohn's Disease in Adults. Am J Gastroenterol. 2018; 113(4):481-517; https://doi.org/10.1038/ajg.2018.27
Nguyen G, Seow C, Maxwell C, Huang V, Leung Y, Jones J, Leontiadis, et al. The Toronto consensus statements for the management of inflammatory bowel disease in pregnancy. Gastroenterology. 2016;150:734-757. https://doi.org/10.1053/j.gastro.2015.12.003
Ludvigsson JF, Lebwohl B, Ekbom A, Pokala-Kiran R, Green PH, Hoijer J, Stephansson O. Outcomes of pregnancies for women undergoing endoscopy while they were pregnant: a nationwide cohort study. Gastroenterology. 2017;152:554-563. https://doi.org/10.1053/j.gastro.2016.10.016
Biancone L, Annese V, Ardizzone S, Armuzzi A, Calabrese E, Caprioli F, et al. Safety of treatments for inflammatory bowel disease: clinical practice guidelines of the Italian Group for the Study of Inflammatory Bowel Disease (IG-IBD). Digest Liver Dis. 2017;49:338-358.
https://doi.org/10.1016/j.dld.2017.01.141
Panayiotis G, Thomas A, Lodhia N. Medical therapy for inflammatory bowel disease. Sur Clin N Am. 2015;95:1159-1182. https://doi.org/10.1016/j.suc.2015.08.004
Cheifetz A, Cullen G. Sulfasalazine and 5-aminosalicylates in the treatment of inflammatory bowel disease. UptoDate [Internet] [Consultado 08 abril 2020] 2020. Disponible en: https://www.uptodate.com/contents/sulfasalazine-and-5-aminosalicylates-in-the-treatment-of-inflammatory-bowel-disease
American college of obstetricians and gynecologists. ACOG Committee Opinion No. 776: Immune modulating therapies in pregnancy and lactation. Obstet Gynecol. 2019;133(4):e287-e295. https://doi.org/10.1097/AOG.0000000000003176
Dingsdag SA, Hunter N. Metronidazole: an update on metabolism, structure-cytotoxicity and resistance mechanisms. J Antimicrob Chemother 2018; 73: 265-279. https://doi.org/10.1093/jac/dkx351
Mahadevan U, McConnell RA, Chambers CD. Drug safety and risk of adverse outcomes for pregnant patients with inflammatory bowel disease. Gastroenterology. 2017;152:451-462. https://doi.org/10.1053/j.gastro.2016.10.013
Acar S, Keskin-Arslan E, Erol-Coskun H, Kaya-Temiz T, Kaplan YC. Pregnancy outcomes following quinolone and fluoroquinolone exposure during pregnancy: a systematic review and meta-analysis. Reproductive Toxicology. 2019;85:65-74. https://doi.org/10.1016/j.reprotox.2019.02.002
Engel T, Yung DE, Ma C, Pariente B, Wlls P, Eliakim R, et al. Effectiveness and safety of ustekinumab for Crohn's disease; systematic review and pooled análisis of real-world evidence. Digest Liver Dis. 2019;51:1232-1240. https://doi.org/10.1016/j.dld.2019.05.002
Matro R, Martin CF, Wolf D, Shah S, Mahadevan U. Exposure concentrations of infants breastfed by women receiving biologic therapies for inflammatory bowel diseases and effects of breastfeeding on infections and development. Gastroenterology. 2018;155:696-704. https://doi.org/10.1053/j.gastro.2018.05.040
Pérez-Jeldres T, Tyler CJ, Boyer JD, Karuppuchamy T, Yarur A, Giles DA. Targeting cytokine signaling and lymphocyte traffic via small molecules in inflammatory bowel disease: JAK inhibitors and S1PR agonists. Front Pharmacol. 2019;10(212):1-15. https://doi.org/10.3389/fphar.2019.00212
Singh S, Allegretti JR. AGA technical review on the management of moderate to severe ulcerative colitis. Gastroenterology. 2020;158:1465-1496. https://doi.org/10.1053/j.gastro.2020.01.007
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