Abstract
Menopause is a natural stage where there is no recipe or protocol to establish the indication of estrogen therapy. The KEEPS study emphasizes the need for hormone replacement therapy. It is an exclusive decision between the doctor and the patient, so it is of vital importance as a doctor to consider their health implications in an individualized way.
Keywords
Hormone replacement therapy. estrogen. estradiol. neurotransmitters. alzheimer.
References
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2. Zandi PP, Carlson MC, Plassman BL, et al. (2002) Hormone replacement therapy and incidence of Alzheimer disease in older women: the Cache County Study. Jama; 288: 21232129.
3. Bhavnani BR. (2003) Estrogens and menopause: pharmacology of conjugated equine estrogens and their potential role in the prevention of neurodegenerative diseases such as Alzheimer's. J Steroid Biochem Mol Biol; 85: 473-482.
4. Sherwin BB. (2009) Estrogen therapy:is time of initiation critical for neuroprotection. Nat RevEndocrinol.620-627.PubMed:19844249.
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6. Erickson Kl, Voss MW, Prakash RS, et al. (2006) A cross-sectional study of hormone treatment and hippocampal volume in postmenopausal women:evidence for a limited window of opportunity. Neuropsychology. 24:68-76. PubMed:3947.
7. Wharton W, Gleason CE, Lorenze KR, et al. (2009) Potential role of estrogen in the pathobiology and prevention of Alzheimer's disease. Amy Transi Res.2:l 31-147.
2. Zandi PP, Carlson MC, Plassman BL, et al. (2002) Hormone replacement therapy and incidence of Alzheimer disease in older women: the Cache County Study. Jama; 288: 21232129.
3. Bhavnani BR. (2003) Estrogens and menopause: pharmacology of conjugated equine estrogens and their potential role in the prevention of neurodegenerative diseases such as Alzheimer's. J Steroid Biochem Mol Biol; 85: 473-482.
4. Sherwin BB. (2009) Estrogen therapy:is time of initiation critical for neuroprotection. Nat RevEndocrinol.620-627.PubMed:19844249.
5. Daniel jM, Bohacek J. (2010) The critical period hypothesis of estrogen effects on cognition:lnsights from basic research. Biochimica et Biophysica Acta. 1800:1068-1076.
6. Erickson Kl, Voss MW, Prakash RS, et al. (2006) A cross-sectional study of hormone treatment and hippocampal volume in postmenopausal women:evidence for a limited window of opportunity. Neuropsychology. 24:68-76. PubMed:3947.
7. Wharton W, Gleason CE, Lorenze KR, et al. (2009) Potential role of estrogen in the pathobiology and prevention of Alzheimer's disease. Amy Transi Res.2:l 31-147.
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