How to Cite
Abstract
Narcolepsy also known as Gelineau syndrome or sleep epilepsy. It is defined as a neurological disease characterized by excessive daytime sleepiness, premature transitions from sleep monitoring with rapid eye movements (REM), paralysis on awakening or sleep paralysis, hypnagogic hallucinations (fleeting visions in the wake-sleep transition) or hypnopompics (sleep-wake transition), fragmented nocturnal sleep and in the case of narcolepsy type 1 suffered from cataplexy (periods in which the individual presents bilateral loss of muscle tone without loss of consciousness), does not occur in type 2. This review is carried out in order to promote knowledge of this pathology for patients, family members and health professionals to obtain an adequate diagnostic and therapeutic approach in this population.
Keywords
References
2. Arias, O. (2009) Sistema hipocretinérgico y narcolepsia. Revista Médica de Chile. 137, 1209-1216.
3. Baccelli, A.; Pedemonte, M. (2013) Narcolepsia, trastorno del sueño subdiagnosticado. Tendencias en Medicina. 42: 96-103.
4. Urrestarazu, E.; Escobar, F. & Iriarte, J. (2015) El sueño y su patología. Medicine - Programa de Formación Médica Continuada Acreditado.11, 4385-4394.
5. Scammell, T. (2015) Narcolepsy. The New England Journal Medicine. 373, 2654-2661.
6. Kasper, D.; Fauci, A.; Hauser, S; Longo, D.; Jameson, J. & Loscalzo, J. (2016). Harrison. Principios de Medicina Interna, 19e ed. McGraw-Hill. 184-190.
7. Santamaría, J. (2012) Actualización diagnóstica y terapéutica en narcolepsia. Revista de Neurología; 54, 25-30.
8. Pabón, R.; García I.; Morales, G.; Urriza, J.; Imirizaldu, L. & Ramos, F. (2010) Narcolepsia: actualización en etiología, manifestaciones clínicas y tratamiento. Anales del Sistema Sanitario de Navarra. Vol. 33, Nº 2, 191-200.
9. Montplaisir, J.; Petit, D.; Quinn, M.; Ouakki, M.; Deceuninck, G.; Desautels, A.; Mignot, E. & De Wals, P. (2014) Risk of Narcolepsy Associated with Inactivated Adjuvanted (AS03) A/H1N1 (2009) Pandemic Influenza Vaccine in Quebec. PLOS ONE. 9, 1-8.
10. Peraita, R. (2015). Narcolepsia con cataplejía (narcolepsia tipo 1). D’genes, Asociación de enfermedades raras. 1-2. Accedido y descargado el 20 de octubre 2018, desde https://www.narcolepsia.org/app/download/24762736/VIII+Congreso+Nacional+de+Enfermedades+Raras.pdf
11. Barateau, L., Lopez, R., & Dauvilliers, Y. (2016). Treatment Options for Narcolepsy. Springer International Publishing Switzerland. 1-8.
12. Lammers, G. (2018) Drugs Used in Narcolepsy and Other Hypersomnias. Sleep Medicine Clinics. 13, 183–189.
13. Merino, A., Hidalgo, V. (2010) Hipersomnia. Somnolencia diurna excesiva y alteraciones del ritmo circadiano en pediatría. Pediatría Integral. XIV (9), 722-724.
14. Romigi, A.; Vitrani, G.; Lo Giudice, T.; Centonze, D.; Franco, V. (2018) Profile of pitolisant in the management of narcolepsy: design, development, and place in therapy. Drug Design, Development and Therapy.12, 2665–2675.
15. Song, H.; Kim, T.; Um, Y. & Hong, S. (2016). Narcolepsy: Association with H1N1 Infection and Vaccination. Sleep Medicine Research. 7(2):43-47.
16. Zhang, J.; Han, F. (2017) Sleepiness in Narcolepsy. Sleep Medicine Clinics. 1-7.