How to Cite
1.
García Rojas C. Hand-foot-mouth disease. Rev.méd.sinerg. [Internet]. 2018Apr.1 [cited 2024Jul.22];3(4):9-12. Available from: https://revistamedicasinergia.com/index.php/rms/article/view/118
Abstract
Hand-foot-mouth disease is one of the most common exanthematic illness in children under five years of age, caused mainly by Coxackie virus A16. Typically it presents consists as a papulo/vesicular rash in hands and feet, associated with oral enanthema. These review is made, aiming to provide the clinician with the tools necessary to recognize clinical manifestations, outpatient management; as well as detect main complications of the disease and the latest in-patient management criteria.
Keywords
Hand-foot-mouth disease. coxackie virus. exanthematic. enanthema.
References
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2. Stelmashook EV, Isaev NK, Zorov DB. Paraquat potentiates glutamate toxicity in immature cultures of cerebellar granule neurons. 2007; (1-3): 82-8.
3. Niso-Santano M, Moran J M, Garcia-Rubio L, GomezMartin A, Gonzalez-Polo R A, Low concentrations of paraquat induces early activation of extracellular signalregulated kinase 1/2, protein kinase B, and c-Jun N-terminal kinase 1/2 pathways: role of c-Jun N-terminal kinase in paraquatinduced cell death. 2006; (2): 507-15.
4. Chen Q, Niu Y, Zhang R, Guo H, Gao Y, The toxic influence of paraquat on hippocampus of mice: involvement of oxidative stress. 2010; (3): 310-6.
5. Peng J, Stevenson FF, Oo ML, Andersen JK. Iron-enhanced paraquat-mediated dopaminergic cell death due to increased oxidative stress as a consequence of microglial activation 2009; Free Radic Biol Med (2): 312-20.
6. Kang MJ, Gil SJ, Koh HC. Paraquat induces alternation of the dopamine catabolic pathways and glutathione levels in the substantia nigra of mice. 2009; (2): 148-52.
7. Ren JP, Zhao YW, Sun XJ. Toxic influence of chronic oral administration of paraquat on nigrostriatal dopaminergic neurons in C57BL/6 mice. 2009; 122 (19): 2366-71.
8. Dart RC, McGuigan MA. Pesticides. 3 ed. Philadelphia: Lippincott Williams and Wilkins; 2004. 1475534.
9. Wu B, Song B, Yang H, Huang B, Chi B, Central nervous system damage due to acute paraquat poisoning: an experimental study with rat model. Neurotoxicology 2013; : 62-70.
10. Wang Q, Liu S, Hu D, Wang Z, Wang L, . Identification of apoptosis and macrophage migration events in paraquatinduced oxidative stress using a zebrafish model. Life.Science 2016; (16): 30365-4
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