Síndrome de Lambert-Eaton paraneoplásico en carcinoma de células pequeñas de pulmón
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González-Houdelath K, Varela Moreno AC, Barrantes Astorga GJ. Síndrome de Lambert-Eaton paraneoplásico en carcinoma de células pequeñas de pulmón. Rev.méd.sinerg. [Internet]. 1 de agosto de 2020 [citado 29 de marzo de 2024];5(8):e562. Disponible en: https://revistamedicasinergia.com/index.php/rms/article/view/562

Resumen

El síndrome miasténico de Lambert Eaton es una patología autoinmune paraneoplásica asociada mayormente a cáncer de pulmón, que se manifiesta con afectación de la unión neuromuscular y disfunciones autonómicas. Se presenta el caso de una paciente femenina de 58 años quien fue diagnosticada con cáncer de pulmón de células pequeñas y que posteriormente presentó la tríada clásica de síndrome miasténico de Lambert Eaton (debilidad proximal de miembros inferiores, disfunción autonómica e hiporreflexia). Se abordó mediante pruebas neurofisiológicas (electromiografía), confirmando su diagnóstico en asociación con el cuadro clínico. El caso presentado a continuación destaca la asociación de neoplasias pulmonares con el diagnóstico de síndrome miasténico de Lambert Eaton y la mejoría de los síntomas gracias al tratamiento sintomático y oncológico.

https://doi.org/10.31434/rms.v5i8.562

Palabras clave

neoplasia de pulmón. síndrome paraneoplásico. autoinmunidad. síndrome miasténico de Lambert-Eaton;. enfermedades de la unión neuromuscular.
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