Síndrome de Lambert-Eaton paraneoplásico en carcinoma de células pequeñas de pulmón

Palabras clave: neoplasia de pulmón, síndrome paraneoplásico, autoinmunidad, síndrome miasténico de Lambert-Eaton;, enfermedades de la unión neuromuscular

Resumen

El síndrome miasténico de Lambert Eaton es una patología autoinmune paraneoplásica asociada mayormente a cáncer de pulmón, que se manifiesta con afectación de la unión neuromuscular y disfunciones autonómicas. Se presenta el caso de una paciente femenina de 58 años quien fue diagnosticada con cáncer de pulmón de células pequeñas y que posteriormente presentó la tríada clásica de síndrome miasténico de Lambert Eaton (debilidad proximal de miembros inferiores, disfunción autonómica e hiporreflexia). Se abordó mediante pruebas neurofisiológicas (electromiografía), confirmando su diagnóstico en asociación con el cuadro clínico. El caso presentado a continuación destaca la asociación de neoplasias pulmonares con el diagnóstico de síndrome miasténico de Lambert Eaton y la mejoría de los síntomas gracias al tratamiento sintomático y oncológico.

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Biografía del autor/a

Dra. Karolina González-Houdelath, Investigadora independiente, San José, Costa Rica

Médica general, graduada de la Universidad de Costa Rica (UCR). cod. MED15826.  Correo: kgh_cr@hotmail.com.

Dra. Ana Cristina Varela Moreno, Investigadora independiente, San José, Costa Rica

Médica general, graduada de la Universidad de Costa Rica (UCR). cod. MED15848. Correo: cvarelam28@gmail.com

Dr. Gerald Josué Barrantes Astorga , Investigador independiente, San José, Costa Rica

Médico general, graduado de la Universidad de Costa Rica (UCR) . cod. MED15899. Correo: geraldba93@gmail.com

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Publicado
2020-08-01
Cómo citar
1.
González-Houdelath K, Varela Moreno AC, Barrantes Astorga GJ. Síndrome de Lambert-Eaton paraneoplásico en carcinoma de células pequeñas de pulmón. Rev.méd.sinerg. [Internet]. 1 de agosto de 2020 [citado 24 de noviembre de 2020];5(8):e562. Disponible en: https://revistamedicasinergia.com/index.php/rms/article/view/562
Sección
Reporte de Casos Clinicos

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