Amniotic fluid embolism, deadly complication in late pregnancy
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Rodríguez Alfaro A, Núñez Segura NM, Echeverri Lohrengel A. Amniotic fluid embolism, deadly complication in late pregnancy. Rev.méd.sinerg. [Internet]. 2022Mar.1 [cited 2024May12];8(3):e955. Available from: https://revistamedicasinergia.com/index.php/rms/article/view/955

Abstract

Amniotic fluid embolism is one of the most catastrophic obstetric complications in the peripartum and postpartum period, corresponding to one of the main causes of maternal mortality. Its incidence varies according to geographical area, with an average of 1.7-1.8 cases per 100,000 pregnant women. When the amniotic fluid enters the maternal circulation, it becomes a puzzle that has not been deciphered with certainty and includes immune responses due to interactions with fetal antigens, coagulopathies, systemic inflammatory response data, alterations at the pulmonary level with edema, congestion and atelectasis, and even anaphylactic shock, among many others. Given a diverse clinical presentation, there are no established diagnostic criteria or laboratory tests, so its diagnosis is mainly clinical, depending on the manifestations presented by the patient or, in the event of her death, pathological evidence can be found. Amniotic fluid embolism should be suspected and identified to achieve rapid management and to reduce maternal and fetal morbidity and mortality.

https://doi.org/10.31434/rms.v8i3.955

Keywords

amniotic fluid embolism. pregnancy. embolism. coagulopathy. maternal mortality.
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