How to Cite
Abstract
Myasthenia Gravis is an autoimmune disease that affects the neuromuscular junction, by blocking it functionally, by producing antibodies against nicotinic receptors. It presents with symptoms of fatigue in different muscle groups, which can affect speech, swallowing and breathing. This pathology is treated with anticholinesterase drugs, corticosteroids and/or thymectomy. Patients with myasthenia gravis have a higher risk of perioperative complications than the general population. Due to this, special care must be taken in the perioperative period. Respiratory failure is a life-threatening complication, so the risks of respiratory muscle weakness should be minimized. the patient are aware of possible complications.
Keywords
References
Yokoyama K, Hattori N. Management of myasthenia gravis in daily practice for general neurologists and healthcare professionals. Clin Exp Neuroimmunol. 2017;8(2):162-70. https://doi.org/10.1111/cen3.12390
Kowalczyk M, Nestorowicz A, Stachurska K, Fijałkowska A, Stążka J. Myasthenia gravis: A careful perioperative anesthetic management of coronary artery bypass grafting. J Neurosci Nurs. 2015;47(3):161-5. https://doi.org/10.1097/JNN.0000000000000138
Kadota Y, Horio H, Mori T, Sawabata N, Goto T, Yamashita S-I, et al. Perioperative management in myasthenia gravis: republication of a systematic review and a proposal by the guideline committee of the Japanese Association for Chest Surgery 2014. Gen Thorac Cardiovasc Surg. 2015;63(4):201-15. https://doi.org/10.1007/s11748-015-0518-y
Muckler VC, O'Brien JM, Matson SE, Rice AN. Perianesthetic implications and considerations for myasthenia gravis. J Perianesth Nurs. 2019;34(1):4-15. https://doi.org/10.1016/j.jopan.2018.03.009
Chang Y-W, Chou Y-C, Yeh C-C, Hu C-J, Hung C-J, Lin C-S, et al. Outcomes after major surgery in patients with myasthenia gravis: A nationwide matched cohort study. PLoS One. 2017;12(6):e0180433. https://doi.org/10.1371/journal.pone.0180433
Dhallu MS, Baiomi A, Biyyam M, Chilimuri S. Perioperative management of neurological conditions. Health Serv Insights. 2017; 10:1178632917711942. https://doi.org/10.1177/1178632917711942
Drachman DB. Myasthenia gravis. Semin Neurol. 2016;36(5):419-24. https://doi.org/10.1055/s-0036-1586265
Akatsu M, Ikegami Y, Tase C, Nishikawa K. Anesthetic management of a patient with antimuscle-specific kinase antibody-positive myasthenia gravis undergoing an open cholecystectomy: A case report: A case report. A A Case Rep. 2017;8(6):150-3. https://doi.org/10.1213/XAA.0000000000000453
Gilhus NE. Myasthenia gravis. N Engl J Med. 2016;375(26):2570-81. https://doi.org/10.1056/NEJMra1602678
Evoli A, Iorio R, Bartoccioni E. Overcoming challenges in the diagnosis and treatment of myasthenia gravis. Expert Rev Clin Immunol. 2016;12(2):157-68. https://doi.org/10.1586/1744666X.2016.1110487
Jing Y, Liu X, Yu L, Li R. Outcomes of preoperative and postoperative corticosteroid therapies in myasthenia gravis. Eur Neurol. 2017;78(1-2):86-92. https://doi.org/10.1159/000478905
Comacchio GM, Marulli G, Mammana M, Natale G, Schiavon M, Rea F. Surgical decision making: Thymoma and myasthenia gravis. Thorac Surg Clin. 2019;29(2):203-13. https://doi.org/10.1016/j.thorsurg.2018.12.007
Xue L, Wang L, Dong J, Yuan Y, Fan H, Zhang Y, et al. Risk factors of myasthenic crisis after thymectomy for thymoma patients with myasthenia gravis. Eur J Cardiothorac Surg. 2017;52(4):692-7. https://doi.org/10.1093/ejcts/ezx163
Vanjari V, Maybauer MO. Anaesthetic management of myasthenia gravis in coronary artery bypass grafting. Ann Card Anaesth. 2020;23(2):209-11.
https://doi.org/10.4103/aca.ACA_176_18
Liu X-Z, Wei C-W, Wang H-Y, Ge Y-H, Chen J, Wang J, et al. Effects of general-epidural anaesthesia on haemodynamics in patients with myasthenia gravis. West Indian Med J. 2015;64(2):99-103. https://doi.org/10.7727/wimj.2013.054
Keating GM. Sugammadex: A review of neuromuscular blockade reversal. Drugs. 2016;76(10):1041-52. https://doi.org/10.1007/s40265-016-0604-1
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
Copyright (c) 2021 Array