Premenstrual dysphoric disorder: evidence-based treatment

Abstract

Premenstrual dysphoric syndrome is a disorder that affects various spheres of life, causing functional impairment. In its etiology, dysregulation of hormones and neurotransmitters is involved, for its diagnosis the criteria of the Diagnostic and Statistical Manual of Mental Disorders, the DSM-V, are used. Antidepressant treatment is considered the first line of treatment; the use of anovulatory agents such as contraceptives and gonadotropin-releasing hormone agonists, can be considered especially in patients who

require fertility control and symptom management. Surgery is considered the last line of treatment for patients with severe and difficult to control symptoms. There are other therapies such as alloprenanolone, cognitive behavioral therapy, diet and exercise that require future research to determine their benefit in the management of this disorder.