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Abstract
Type 1 diabetes mellitus is a disease, being a highly prevalent disease in the pediatric population, of complex autoimmune etiology, characterized by destruction of pancreatic beta cells in genetically predisposed individuals and the consequent deficiency in insulin production and hyperglycemia. The diagnosis is based on clinical features and laboratory findings. The key element of treatment for optimal glycemic control is an intensive multiple-dose insulin regimen. Despite this, most patients have suboptimal glycemic control, which has led to the investigation and identification of possible factors involved in suboptimal control of the disease.
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References
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