Crohn's disease: a comprehensive approach to its pathogenesis, diagnosis, and treatment
PDF (Español (España))
HTML (Español (España))
صندلی اداری سرور مجازی ایران Decentralized Exchange

How to Cite

1.
Sánchez Bonilla E, Wong Álvarez Óscar F, Fung Cai M. Crohn’s disease: a comprehensive approach to its pathogenesis, diagnosis, and treatment. Rev.méd.sinerg. [Internet]. 2023Aug.1 [cited 2024May13];8(8):e1092. Available from: https://revistamedicasinergia.com/index.php/rms/article/view/1092

Abstract

Crohn's disease is a chronic inflammatory condition of the gastrointestinal tract that can affect any part of the digestive system, from the mouth to the anus. The pathogenesis of the disease involves a combination of genetic, environmental, and immunological factors that lead to chronic inflammation and damage to intestinal tissue. Symptoms can vary and can include abdominal pain, diarrhea, weight loss, and fatigue. Diagnosis is made using a combination of diagnostic tools and tests, such as colonoscopy, computed tomography, and magnetic resonance imaging. Treatment focuses on symptom control and may include immunosuppressive drugs, diet and lifestyle changes, and in some cases, surgery. The prognosis can vary, and complications can include intestinal obstruction, fistulas, abscesses, and bowel cancer. Continued research is important to improve the understanding and treatment of Crohn's disease.

https://doi.org/10.31434/rms.v8i8.1092

Keywords

Crohn's disease. inflammatory bowel disease. chronic inflammation. abdominal pain. colonoscopy.
PDF (Español (España))
HTML (Español (España))

References

Roda G, Chien Ng S, Kotze PG, Argollo M, Panaccione R, Spinelli A, et al. Crohn’s disease. Nat Rev Dis Primers [Internet]. 2020 [citado el 25 abril 2023];6(1):22. Disponible en: http://dx.doi.org/10.1038/s41572-020-0156-2

Ballester Ferré MP, Boscá-Watts MM, Mínguez Pérez M. Enfermedad de Crohn. Med Clin (Barc) [Internet]. 2018 [citado el 25 de abril, 2023];151(1):26–33. Disponible en: http://dx.doi.org/10.1016/j.medcli.2017.10.036

Gajendran M, Loganathan P, Catinella AP, Hashash JG. A comprehensive review and update on Crohn’s disease. Dis Mon [Internet]. 2018 [citado el 25 abril 2023];64(2):20–57. Disponible en: http://dx.doi.org/10.1016/j.disamonth.2017.07.001

Tsai L, McCurdy JD, Ma C, Jairath V, Singh S. Epidemiology and natural history of perianal Crohn’s disease: A systematic review and meta-analysis of population-based cohorts. Inflamm Bowel Dis [Internet]. 2022 [citado el 25 abril 2023];28(10):1477–84. Disponible en: http://dx.doi.org/10.1093/ibd/izab287

Petagna L, Antonelli A, Ganini C, Bellato V, Campanelli M, Divizia A, et al. Pathophysiology of Crohn’s disease inflammation and recurrence. Biol Direct [Internet]. 2020 [citado el 25 abril 2023]. 15(1):23. Disponible en: http://dx.doi.org/10.1186/s13062-020-00280-5

Hansen T, Duerksen DR. Enteral nutrition in the management of pediatric and adult crohn’s disease. Nutrients [Internet]. 2018 [citado el 25 abril 2023];10(5). Disponible en: http://dx.doi.org/10.3390/nu10050537

Crespi M, Dulbecco P, De Ceglie A, Conio M. Strictures in Crohn’s disease: From pathophysiology to treatment. Dig Dis Sci [Internet]. 2020 [citado el 25 abril 2023];65(7):1904–16. Disponible en: http://dx.doi.org/10.1007/s10620-020-06227-0

Rogler G, Singh A, Kavanaugh A, Rubin DT. Extraintestinal manifestations of inflammatory bowel disease: Current concepts, treatment, and implications for disease management. Gastroenterology [Internet]. 2021 [citado el 25 abril 2023];161(4):1118–32. Disponible en: http://dx.doi.org/10.1053/j.gastro.2021.07.042

Qari YA. Clinical characteristics of Crohn’s disease in a cohort from Saudi Arabia. Saudi J Med Med Sci [Internet]. 2022 [citado el 25 abril 2023];10(1):56–62. Disponible en: http://dx.doi.org/10.4103/sjmms.sjmms_35_20

Gergely M, Deepak P. Tools for the diagnosis and management of Crohn’s disease. Gastroenterol Clin North Am [Internet]. 2022 [citado el 25 abril 2023];51(2):213–39. Disponible en: http://dx.doi.org/10.1016/j.gtc.2021.12.003

Vale Rodrigues R, Sladek M, Katsanos K, van der Woude CJ, Wei J, Vavricka SR, et al. Diagnosis and outcome of oesophageal crohn’s disease. J Crohns Colitis [Internet]. 2020 [citado el 25 abril 2023];14(5):624–9. Disponible en: http://dx.doi.org/10.1093/ecco-jcc/jjz201

Guimarães LS, Greer M-LC, Dillman JR, Fletcher JG. Magnetic resonance in crohn’s disease: Diagnosis, disease burden, and classification. Magn Reson Imaging Clin N Am [Internet]. 2020 [citado el 25 abril 2023].28(1):31–44. Disponible en: http://dx.doi.org/10.1016/j.mric.2019.08.003

Shen B, Kochhar GS, Rubin DT, Kane SV, Navaneethan U, Bernstein CN, et al. Treatment of pouchitis, Crohn’s disease, cuffitis, and other inflammatory disorders of the pouch: consensus guidelines from the International Ileal Pouch Consortium. Lancet Gastroenterol Hepatol [Internet]. 2022 [citado el 25 abril 2023];7(1):69–95. Disponible en: http://dx.doi.org/10.1016/S2468-1253(21)00214-4

Cushing K, Higgins PDR. Management of Crohn disease: A review. JAMA [Internet]. 2021 [citado el 25 abril 2023]. 325(1):69–80. Disponible en: http://dx.doi.org/10.1001/jama.2020.18936

Caio G, Lungaro L, Caputo F, Zoli E, Giancola F, Chiarioni G, et al. Nutritional treatment in crohn’s disease. Nutrients [Internet]. 2021 [citado el 25 abril 2023];13(5):1628. Disponible en: http://dx.doi.org/10.3390/nu13051628

Zhang C, Yu D, Hong L, Zhang T, Liu H, Fan R, et al. Prevalence of sarcopenia and its effect on postoperative complications in patients with Crohn’s disease. Gastroenterol Res Pract [Internet]. 2021 [citado el 25 abril 2023];2021:3267201. Disponible en: http://dx.doi.org/10.1155/2021/3267201

Guizzetti L, Zou G, Khanna R, Dulai PS, Sandborn WJ, Jairath V, et al. Development of clinical prediction models for surgery and complications in Crohn’s disease. J Crohns Colitis [Internet]. 2018 [citado el 25 abril 2023];12(2):167–77. Disponible en: http://dx.doi.org/10.1093/ecco-jcc/jjx130

Betancur Salazar K, Mosquera-Klinger G. Crohn’s disease with esophagogastroduodenal involvement. Rev Gastroenterol Méx (Engl Ed) [Internet]. 2020 [cited May 12, 2023];85(4):481–4. Disponible en: http://dx.doi.org/10.1016/j.rgmx.2019.10.002

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

Copyright (c) 2023 Array

Downloads

Download data is not yet available.
فروشگاه اینترنتی صندلی اداری جوراب افزایش قد ژل افزایش قد صندلی اداری