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La sepsis es un proceso infeccioso altamente inflamatorio que se asocia con una incidencia importante de mortalidad y múltiples complicaciones. Una de estas complicaciones es la coagulación intravascular diseminada que se desarrolla en casi la mitad de los pacientes con sepsis. Esta tiene como una de sus consecuencias finales la falla orgánica múltiple, por lo cual no es extraño que la tasa de mortalidad de un paciente con sepsis y coagulación intravascular diseminada sea relativamente alta. La patogénesis de la coagulación intravascular diseminada puede ser atribuida a un trastorno de coagulación iniciado por el factor tisular, con diseminación de micro coágulos y consumo acelerado de factores de coagulación. Tiene entonces como resultado, la falla orgánica múltiple, diferentes trastornos hemorrágicos y en los peores casos, la muerte. El manejo actual de la coagulación intravascular diseminada está dirigido a tratar la enfermedad subyacente, en este caso el agente patógeno, además del tratamiento anticoagulante de soporte para mejorar los resultados clínicos.
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