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Abstract
Eosinophilic esophagitis is a chronic inflammatory disease of the esophagus that occurs due to an immunoallergic response triggered in most cases by food antigens. Clinically it is characterized by signs and symptoms related to esophageal dysfunction and histologically by tissue inflammation in which eosinophils predominate. Eosinophilic eophagitis is diagnosed when there are symptoms related to esophageal dysfunction such as dysphagia and food impaction, the presence of ≥15 eosinophils per high-power field on esophageal mucosal biopsy, and after a thorough evaluation for disorders that may cause or contribute to esophageal eosinophilia. The treatment consists of dietary modifications, pharmacological therapies and endoscopic interventions. In 2022, dupilumab became the first Food and Drug Administration -approved treatment for eosinophilic esophagitis. The importance of health personnel dealing with this disease lies in the fact that although it is a chronic disease, its early and timely diagnosis improves the evolution of the disease and the quality of life of the patient's treatment.
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References
Nhu QM, Aceves SS. Current state of biologics in treating eosinophilic esophagitis. Ann Allergy Asthma Immunol. 2022, Oct 12:S1081-1206(22)01830-0. Doi: https://doi.org/10.1016/j.anai.2022.10.004
Stave Salgado KV, Rocca AM. Eosinophilic esophagitis and esophageal atresia: coincidence or causality? Arch Argent Pediatr. 2018, Feb 01;116(1):e61-e69. English, Spanish. Doi: https://doi.org/10.5546/aap.2018.eng.e61
Pérez-Martínez I, Rodrigo L, Lucendo AJ. Eosinophilic esophagitis: An evidenced-based approach to diagnosis and treatment. Med Clin. 2019, Jun 07;152(11):444-449. English, Spanish. Doi: https://doi.org/10.1016/j.medcli.2018.10.022
Gutiérrez C, Fernández S, Domínguez-Ortega G, Vila V, García R, García R, et al. Recomendaciones para el diagnóstico y manejo práctico de la esofagitis eosinofílica pediátrica. An Pediatr. Junio 2020;92(6):376.e1-376.e10. Doi: https://doi.org/10.1016/j.anpedi.2020.04.007
Lucendo AJ, Molina-Infante J. Eosinophilic oesophagitis: Current evidence-based diagnosis and treatment. Gastroenterol Hepatol. 2018 Apr;41(4):281-291. English, Spanish. Doi: https://doi.org/10.1016/j.gastrohep.2017.12.007
Miret-Salvador M, Valor-Gisbert M, Ruiz-Lozano N, Gracia-Barber MD. Esofagitis eosinofílica. Un caso clínico no tan raro [Eosinophilic esophagitis. A not so rare clinical case]. Semergen. Marzo 2022;48(2):124-128. Doi: https://doi.org/10.1016/j.semerg.2021.04.012
Shah MZ, Polk BI. Eosinophilic Esophagitis: The Role of Environmental Exposures. Immunol Allergy Clin North Am. 2022, Nov; 42(4):761-770. Doi: https://doi.org/10.1016/j.iac.2022.05.006
Macías F, Domínguez, JE. Esofagitis eosinofílica y esofagitis infecciosas y tóxicas. Medicine. 2020;13(7):384–391. Doi: https://doi.org/10.1016/j.med.2020.05.003
Lehman HK, Lam W. Eosinophilic Esophagitis. Immunology and Allergy Clinics of North America. 2021;41(4):587-598. Doi: https://doi.org/10.1016/j.iac.2021.07.011
Kumar S, Choi SS, Gupta SK. Eosinophilic esophagitis: current status and future directions. Pediatr Res. 2020;88:345–347. Doi: https://doi.org/10.1038/s41390-020-0770-4
Ballart MJ, Monrroy H, Iruretagoyena M, Parada A, Torres J, Espino A. Esofagitis eosinofílica: diagnóstico y manejo [Diagnosis and management of eosinophilic esophagitis]. Rev Med Chil. Junio, 2020;148(6):831-841. Doi: https://doi.org/10.4067/S0034-98872020000600831
Rojas NA, Morfin BM, Chanona-Vilchis J. Throat clearing as the only symptom of eosinophilic esophagitis: A case report. Rev Gastroenterol Mex (Engl Ed). 2020, Apr-Jun;85(2):216-218. Doi: https://doi.org/10.1016/j.rgmx.2019.04.003
Aceves SS, Alexander JA, Baron TH, Bredenoord AJ, Day L, Dellon ES et al. Endoscopic approach to eosinophilic esophagitis: American Society for Gastrointestinal Endoscopy Consensus Conference. Gastrointestinal Endoscopy. 2020;96(4):576-592. Doi: https://doi.org/10.1016/j.gie.2022.05.013
Nhu QM, Aceves SS. Medical and dietary management of eosinophilic esophagitis. Ann Allergy Asthma Immunol. 2018, Aug;121(2):156-161. Doi: https://doi.org/10.1016/j.anai.2018.05.006
Nhu QM, Moawad FJ. New Developments in the Diagnosis and Treatment of Eosinophilic Esophagitis. Curr Treat Options Gastroenterol. 2019, Mar;17(1):48-62. Doi: https://doi.org/10.1007/s11938-019-00216-7
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