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Abstract
Transfusion Acute Lung Injury (TRALI) is a serious and life-threatening syndrome. The FDA has reported that TRALI is the leading cause of transfusion-related deaths for many years, with 34% of TRALI fatalities (64/186 reported transfusion-related deaths between 2012 and 2016). The association between human neutrophil antigen (HNA) or human leukocyte antigen (HLA) found in antibodies in donor blood is associate to TRALI and TACO syndromes. With suggestive symptoms within 6 hours after a blood transfusion and infiltrates on a chest radiograph indicating the presence of pulmonary edema. This syndrome has improved a lot over the last two decades, measures to mitigate the risk of TRALI have been implemented around the world.
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References
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