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Abstract
Chagas’ disease or American tripanosomiasis is a zoonosis product of the infection by the protozoan Trypanosoma cruzi. As its name suggests the disease it is native to America, affecting aproximately 5.7 million people and causing some 20 thousand deaths per year. It is also the third most common parasitosis, only surpassed by malaria and shistosoma. Infection is lifelong in the absence of an adequate and early treatment.
Keywords
References
Bern C. Chagas’ Disease. Longo DL. New England Journal of Medicine. 2015 07 30;373(5):456-466. https://doi.org/10.1056/nejmra1410150
Morillo CA, Marin-Neto JA, Avezum A, Sosa-Estani S, Rassi A, Rosas F, Villena E, Quiroz R, Bonilla R, Britto C, Guhl F, Velazquez E, Bonilla L, Meeks B, Rao-Melacini P, Pogue J, Mattos A, Lazdins J, Rassi A, Connolly SJ, Yusuf S. Randomized Trial of Benznidazole for Chronic Chagas’ Cardiomyopathy. New England Journal of Medicine. 2015 Oct;373(14):1295-1306. https://doi.org/10.1056/nejmoa1507574
Repetto EC, Zachariah R, Kumar A, Angheben A, Gobbi F, Anselmi M, Al Rousan A, Torrico C, Ruiz R, Ledezma G, Buoninsegna MC, Khogali M, Van den Bergh R, De Maio G, Egidi AM, Maccagno B, Garelli S. Neglect of a Neglected Disease in Italy: The Challenge of Access-to-Care for Chagas Disease in Bergamo Area. Rodrigues MM. PLOS Neglected Tropical Diseases. 2015 09 25;9(9):e0004103. https://doi.org/10.1371/journal.pntd.0004103
Longo D. et al. Harrison, Principios de Medicina Interna. Enfermedad de Chagas y Tripanosomiasis. Edición 19; 2016
Lowell A. Goldsmith et al. Fitzpatrick's Dermatology In General Medicine. Chagas'Disease. Eight Edition;2015
Pinazo M, Espinosa G, Cortes-Lletget C, Posada EDJ, Aldasoro E, Oliveira I, Muñoz J, Gállego M, Gascon J. Immunosuppression and Chagas Disease: A Management Challenge. Rodrigues MM. PLoS Neglected Tropical Diseases. 2013 01 17;7(1):e1965. https://doi.org/10.1371/journal.pntd.0001965
PedroAlbajar-Viñas,etat.Advancing the Treatment for Chagas' Disease. N Engl J Med 2014; 370:1942-1943, May 15, 2014.
https://doi.org/10.1056/NEJMe1403688
Albajar-Viñas P, Dias JCP. Advancing the Treatment for Chagas' Disease. New England Journal of Medicine. 2014 05 15;370(20):1942-1943. https://doi.org/10.1056/nejme1403689
Bern C. Antitrypanosomal Therapy for Chronic Chagas' Disease. New England Journal of Medicine. 2011 06 30;364(26):2527-2534. https://doi.org/10.1056/nejmct1014204
Quijano-Hernandez I, Dumonteil E. Advances and challenges towards a vaccine against Chagas disease. Human Vaccines. 2011 Nov;7(11):1184-1191. https://doi.org/10.4161/hv.7.11.17016
Machado MPR, Rocha AM, de Oliveira LF, de Cuba MB, de Oliveira Loss I, Castellano LR, Silva MV, Machado JR, Nascentes GAN, Paiva LH, Savino W, Junior VR, Brum PC, Prado VF, Prado MAM, Silva EL, Montano N, Ramirez LE, Dias da Silva VJ. Autonomic nervous system modulation affects the inflammatory immune response in mice with acute Chagas disease. Experimental Physiology. 2012 Oct 29;97(11):1186-1202. https://doi.org/10.1113/expphysiol.2012.066431
Muñoz SG, Haberland A, Bartel S, Araujo R, Valda G, Duchen D, et al. Cardiac Troponin T Measured With a Highly Sensitive Assay for Diagnosis and Monitoring of Heart Injury in Chronic Chagas Disease. Arch Pathol Lab Med. 2016;(135):243-8.
Santos FM, Lima WG, Gravel AS, Martins TAF, Talvani A, Torres RM, Bahia MT. Cardiomyopathy prognosis after benznidazole treatment in chronic canine Chagas' disease. Journal of Antimicrobial Chemotherapy. 2012 05 07;67(8):1987-1995. https://doi.org/10.1093/jac/dks135
Bern C. Chagas disease in the immunosuppressed host. Current Opinion in Infectious Diseases. 2012 08;25(4):450-457. https://doi.org/10.1097/qco.0b013e328354f179
Maya JD, Orellana M, Ferreira J, Kemmerling U, López-Muñoz R, Morello A. Chagas disease: Present status of pathogenic mechanisms and chemotherapy. Biological Research. 2010;43(3). https://doi.org/10.4067/s0716-97602010000300009
Machado FS, Jelicks LA, Kirchhoff LV, Shirani J, Nagajyothi F, Mukherjee S, et al. Chagas heart disease: report on recent developments. Cardiol Rev. 2014;20(2):53-65.