Evaluation of the therapy applied to symptomatic post-COVID patients, referred to the cardiology service. Lima Perú
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Infante R. Evaluation of the therapy applied to symptomatic post-COVID patients, referred to the cardiology service. Lima Perú. Rev.méd.sinerg. [Internet]. 2024Aug.1 [cited 2024Oct.19];9(8):e1173. Available from: https://revistamedicasinergia.com/index.php/rms/article/view/1173

Abstract

The management of the SARS CoV2 pandemic, which emerged in 2020, imposed a level of demand on health personnel that had not been experienced in the last 100 years, not only due to the volume of cases, but also due to the difficulties in diagnosing and treatment. The interest in knowing the pathophysiology of post-COVID-19 symptoms and determining the influence of inflammation on them led to the performance of a descriptive observational clinical study with 125 outpatients, finding, in most of the patients, the persistence of the bronchus-alveolar and systemic inflammatory process, which determined the appearance of symptoms after infection by the biological particle, as well as showed the satisfactory evolution of those who were treated with Deflazacort at a dose of 6 mg per day in combination with inhaled fluticasone, as observed when evaluating the patients' conditions in terms of oxygen saturation, exertional dyspnea, hemodynamic parameters; such as blood pressure, heart rate and other symptoms such as polyarthralgias related to the normalization of inflammatory parameters such as ESR and CRP; allowing us to conclude that the use of steroids helps control the post-COVID-19 inflammatory process and therefore favors the resolution of these symptoms.

 

https://doi.org/10.31434/rms.v9i8.1173

Keywords

COVID-19. inflammasome. post-COVID complications. Deflazacort. fluticasone.
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