Pacientes víctimas de los imitadores, linfoma cutáneo difuso primario de células B, tipo pierna

Palabras clave: linfoma, úlcera de la pierna, radioterapia, rituximab

Resumen

El linfoma cutáneo primario difuso de células grandes B, tipo pierna es una patología rara y poco conocida, suele presentar como síntoma principal lesiones en piel de las piernas, estas lesiones varían desde nódulos, tumores o placas de color violáceo, frecuentemente se presentarse en mujeres de edad avanzada. A diferencia de otras entidades de este grupo se caracteriza por ser agresivo con la capacidad de infiltrar otros órganos, su base de tratamiento son los quimioterapéuticos asociado a radioterapia y en ocasiones cirugía. 

Estadistica de descarga del artículo

Cargando métricas ...

Biografía del autor/a

Dra. Erika Núñez Picado, Investigadora independiente, San José, Costa Rica

Médica general, graduada de la Universidad de Ciencias Medicas (UCIMED), cod. MED15313. Correo: eka91@me.com

Dra. Génesis Chaverri Padilla, Investigadora independiente, San José, Costa Rica

Médica general, graduada de la Universidad de Ciencias Medicas (UCIMED), cod.MED15236. Correo: genesisc10@gmail.com

Dr. José Rodolfo Elizondo Valverde, Investigador Independiente, Alajuela, Costa Rica

Médico general, graduado de la Universidad de Ciencias Médicas (UCIMED). cod. MED15332. Correo: jr10_04@hotmail.com

Citas

Willemze R, Cerroni L, Kempf W, Berti E, Facchetti F, Swerdlow S et al. The 2018 update of the WHO-EORTC classification for primary cutaneous lymphomas. Blood [Internet]. 2019 [cited 27 February 2020];133(16):1703-1714. https://doi.org/10.1182/blood-2018-11-881268

Campollo I, Socarrás M, Castro A. Linfoma cutáneo de células B grande de las piernas: presentación de un caso. AMC [Internet]. 2011 Dic [citado 2020 Mar 03] ; 15( 6 ): 1037-1045. Disponible en: http://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S1025-02552011000600011&lng=es

Morales C, Damiano S, Bertini D, et al. Linfoma cutáneo primario difuso de células B grandes tipo pierna: primer reporte de presentación como úlcera de Marjolin sobre úlcera venosa crónica. Rev. Méd. Urug. [Internet]. 2015 Mar [citado 2020 Mar 04] ; 31( 1 ): 58-63. Disponible en: http://www.scielo.edu.uy/scielo.php?script=sci_arttext&pid=S1688-03902015000100009&lng=es

Decousus H, Frappé P, Accassat S, Bertoletti L, Buchmuller A, Seffert B et al. Epidemiology, diagnosis, treatment and management of superficial-vein thrombosis of the legs. Best Practice & Research Clinical Haematology [Internet]. 2012 [cited 27 February 2020];25(3):275-284. https://doi.org/10.1016/j.beha.2012.07.005

Lozano., I.; Ríos., A, Della, Giovanna., P.; García., S.: Linfoma pri- mario cutáneo difuso de células B grandes, tipo pierna. Dermatol Argent 2014; 20: 119-122. http://docs.bvsalud.org/biblioref/2018/09/913718/01martinez-linfoma-cutaneo-primario-de-celulas-b-tipo-pierna.pdf

van Galen J, Hoefnagel J, Vermeer M, Willemze R, Dijkman R, Tensen C et al. Profiling of apoptosis genes identifies distinct types of primary cutaneous large B cell lymphoma. The Journal of Pathology [Internet]. 2008 [cited 6 May 2020];215(3):340-346. https://doi.org/10.1002/path.2374

Senff N, Hoefnagel J, Jansen P, Vermeer M, van Baarlen J, Blokx W et al. Reclassification of 300 Primary Cutaneous B-Cell Lymphomas According to the New WHO-EORTC Classification for Cutaneous Lymphomas: Comparison With Previous Classifications and Identification of Prognostic Markers. Journal of Clinical Oncology [Internet]. 2007 [cited 6 May 2020];25(12):1581-1587. https://doi.org/10.1200/JCO.2006.09.6396

Mondal S, Roy S, Mandal P, Biswas P. Primary cutaneous large B-cell lymphoma, leg type: Report of two cases and review of literature. Indian Journal of Medical and Paediatric Oncology [Internet]. 2012 [cited 11 March 2020];33(1):54. https://doi.org/10.4103/0971-5851.96973

Matina M, Gianpaolo T, Chiara C. Incidence and ten-year follow-up of primary cutaneous lymphomas: a single-centre cohort study. Eur J Dermatol [Internet]. 2018 [cited 11 March 2020];28(1):44-49. Available from: https://www.ncbi.nlm.nih.gov/pubmed/29171395

A Patsatsi, A Kyriakou, V Karavasilis, et al.Primary cutaneous diffuse large B-cell lymphoma, leg type, with multiple local relapses: case presentation and brief review of literature. Hippokratia [Internet]. 2013 [cited 11 March 2020];17(2):174-176. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3743626/

Lima M. Cutaneous primary B-cell lymphomas: from diagnosis to treatment. Anais Brasileiros de Dermatologia [Internet]. 2015 [cited 11 April 2020];90(5):687-706. https://doi.org/10.1590/abd1806-4841.20153638

Hope C, Pincus L. Primary Cutaneous B-cell Lymphomas. Clinics in Laboratory Medicine [Internet]. 2017 [cited 11 April 2020];37(3):547-574. https://doi.org/10.1016/j.cll.2017.05.009

Bargot M, Stalder R. Cutaneous lymphoma. In: Wolff K, Goldsmith L, Katz SI. Fitzpatrick's dermatology in general medicine. 9ma ed. Nueva York: McGraw-Hill. 2018. p. 2072-2100.

Nicolay J, Wobser M. Cutaneous B-cell lymphomas - pathogenesis, diagnostic workup, and therapy. JDDG: Journal der Deutschen Dermatologischen Gesellschaft [Internet]. 2016 [cited 21 March 2020];14(12):1207-1224. https://doi.org/10.1111/ddg.13164

Billero V, LaSenna C, Romanelli M, Giubellino A, Brenes R, Romanelli P. Primary cutaneous diffuse large B-cell lymphoma presenting as chronic non-healing ulcer. International Wound Journal [Internet]. 2017 [cited 11 April 2020];14(5):830-832.

https://doi.org/10.1111/iwj.12716

Süß A, Simon J, Sticherling M. Primary Cutaneous Diffuse Large B-cell Lymphoma, Leg Type, with the Clinical Picture of Chronic Venous Ulceration. Acta Dermato-Venereologica [Internet]. 2007 [cited 11 April 2020];87(2):169-170. https://doi.org/10.2340/00015555-0202

Brouillard C, Granel-Brocard F, Montagne K, Bastien C, Barbaud A, Schmutz J. Une présentation atypique de lymphome cutané B primitif à grandes cellules de type jambe. Annales de Dermatologie et de Vénéréologie [Internet]. 2011 [cited 11 April 2020];138(8-9):601-604. https://doi.org/10.1016/j.annder.2011.02.020

Wilcox R. Cutaneous B-cell lymphomas: 2016 update on diagnosis, risk-stratification, and management. American Journal of Hematology [Internet]. 2016 [cited 11 April 2020];91(10):1052-1055. https://doi.org/10.1002/ajh.24462

Rozati S, Kempf W, Ostheeren-Michaelis S, Bode-Lesniewska B, Zimmermann D, Dummer R et al. Cutaneous Diffuse Large B-Cell Lymphoma, Leg Type, With Bilateral Intraocular Involvement and Infiltration to the CNS. Journal of Clinical Oncology [Internet]. 2016 [cited 11 April 2020];34(11):e93-e96. https://doi.org/10.1200/JCO.2013.51.6559

Muniesa C, Pujol R, Estrach M, Gallardo F, García-Muret M, Climent J et al. Primary cutaneous diffuse large B-cell lymphoma, leg type and secondary cutaneous involvement by testicular B-cell lymphoma share identical clinicopathological and immunophenotypical features. Journal of the American Academy of Dermatology [Internet]. 2012 [cited 11 April 2020];66(4):650-654. https://doi.org/10.1016/j.jaad.2011.03.031

Hope C, Pincus L. Primary cutaneous B-cell lymphomas with large cell predominance-primary cutaneous follicle center lymphoma, diffuse large B-cell lymphoma, leg type and intravascular large B-cell lymphoma. Seminars in Diagnostic Pathology [Internet]. 2017 [cited 11 April 2020];34(1):85-98. https://doi.org/10.1053/j.semdp.2016.11.006

Swerdlow S, Quintanilla-Martinez L, Willemze R, Kinney M. Cutaneous B-Cell Lymphoproliferative Disorders. American Journal of Clinical Pathology [Internet]. 2013 [cited 21 March 2020];139(4):515-535. https://doi.org/10.1309/AJCPNLC9NC9WTQYY

Brenner I, Roth S, Puppe B, Wobser M, Rosenwald A, Geissinger E. Primary cutaneous marginal zone lymphomas with plasmacytic differentiation show frequent IgG4 expression. Modern Pathology [Internet]. 2013 [cited 21 March 2020];26(12):1568-1576. https://doi.org/10.1038/modpathol.2013.106

S, Campo E, Pileri S, Harris N, Stein H, Siebert R et al. The 2016 revision of the World Health Organization classification of lymphoid neoplasms. Blood [Internet]. 2016 [cited 22 March 2020];127(20):2375-2390. https://doi.org/10.1182/blood-2016-01-643569

Haverkos B, Tyler K, Gru A, Winardi F, Frederickson J, Hastings J et al. Primary Cutaneous B‐Cell Lymphoma: Management and Patterns of Recurrence at the Multimodality Cutaneous Lymphoma Clinic of The Ohio State University. The Oncologist [Internet]. 2015 [cited 12 April 2020];20(10):1161-1166. https://doi.org/10.1634/theoncologist.2015-0175

Hamilton S, Wai E, Tan K, Alexander C, Gascoyne R, Connors J. Treatment and Outcomes in Patients With Primary Cutaneous B-Cell Lymphoma: The BC Cancer Agency Experience. International Journal of Radiation Oncology*Biology*Physics [Internet]. 2013 [cited 21 March 2020];87(4):719-725. https://doi.org/10.1016/j.ijrobp.2013.07.019

Publicado
2020-10-01
Cómo citar
1.
Núñez Picado E, Chaverri Padilla G, Elizondo Valverde JR. Pacientes víctimas de los imitadores, linfoma cutáneo difuso primario de células B, tipo pierna . Rev.méd.sinerg. [Internet]. 1 de octubre de 2020 [citado 26 de octubre de 2020];5(10):e459. Disponible en: https://revistamedicasinergia.com/index.php/rms/article/view/459
Sección
Artículos de Revisión

Artículos más leídos del mismo autor/a